Conolidine’s analgesic outcomes stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors in the central anxious program, conolidine modulates alternate molecular targets. A Science Developments review observed that conolidine interacts While using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabil... https://conolidine-treat-knee-pai12173.alltdesign.com/alternative-natural-pain-relief-to-replace-traditional-painkillers-an-overview-57564249